The team is aware of a number of players that are having issues in which the mouse is not locking to the screen during gameplay. As a result of this players looking up and down in gameplay may find their taskbar appear. Below are some fixes which should solve the issue for you.
Fix#1
1. Press the Windows key
2. Type User Account Control and press enter
3. Press OK as illustrated in the image below.
4. Reboot your PC.
Your mouse cursor issue should now be resolved.
RARE does not recommend lowering your security settings for whatever reason. Please create a ticket to the Sea of Thieves Support team should your issue not be resolved.
Fix#2
1. Press Windows button + R to open the Run dialog box
2. Type gpedit.msc and press enter
3. From the Folders on the left select Computer Configuration> Administrative Templates> Windows Components> Edge UI
4. Once viewing the Edge UI options right click 'Allow Edge Swipe' and select Edit
5. From the top left corner click Disabled and then press OK
6. Close the Local Group Policy Editor window and boot Sea of Thieves.
Fix#3
1. Open the run command window (Win + R)
2. Type 'regedit' and press ENTER
3. Navigate to 'Computer\HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\'
4. If it doesn't exists, right click the editor background and select Add> Key. Change the name to 'EdgeUI'
5. Navigate to 'EdgeUI' key, right click the editor background and select Add> DWORD (32bit value), change the name to 'AllowEdgeSwipe' and set it to 0
6. Close the Local Group Policy Editor window and boot Sea of Thieves.